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Risk factors for the development of asthma after the neonatal period in high-risk infants with meconium ileus: a population-based study.
Children with meconium ileus (MI) are at risk for the development of asthma, presumably due to persistent inflammation. However, the extent to which these infants pose a risk for the development of asthma is unknown. To determine the risk of developing asthma among high-risk infants with MI, we examined a population-based cohort of 16,937 children up to the age of 16 years using the British Columbia Childhood Asthma Management Program. Children were categorized based on the presence of MI in the first month of life as the primary risk factor. All other children with asthma, eczema, or allergic rhinitis at 2 years of age were considered at risk for developing asthma. Asthma was diagnosed using American Thoracic Society criteria. We used logistic regression models to estimate the association between the primary risk factor of MI and the development of asthma. The median (interquartile range) age of diagnosis of asthma was 11.9 (10.3-13.2) years and median follow-up was 10.6 (9.9-11.2) years. In total, 453 children had MI and 3011 children were at risk for asthma. The risk of developing asthma was increased significantly among children with MI compared with children at risk for asthma only (odds ratio [OR], 2.1; 95% confidence interval [CI], 1.6-2.7). Children with asthma had a significantly greater risk of developing asthma after an MI than those without asthma (OR, 2.6; 95% CI, 1.9-3.6). Asthma risk increased with time since MI. Asthma risk was greatest in the first year after MI (OR, 3.7; 95% CI, 2.2-6.2). The presence of MI, but not later treatment for MI, was associated with the development of asthma. The earliest time after MI when the highest risk for asthma was observed was the first year after MI.Basal cell carcinoma: an unusual case of metastatic basal cell carcinoma to the gallbladder.
Metastatic basal cell carcinoma to the gastrointestinal tract is an extremely rare finding.
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sure how it works. Just use the results from the original link?
Next week we'll be revealing a new set of mods for Destiny 2 which are yet to be announced. It's time to cover off the most exciting part of any Destiny 2 update, the Mod World Update.
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